tadalafil tadalista 40 mg is a generic medication that is used to treat erectile dysfunction (ED) in men. It helps improve sexual satisfaction by providing a normal erection. The medicine works by enhancing the blood flow to the penis. This increases a man's ability to get an erection and makes it easier for him to have sex with his partner. It also reduces the pain caused by ED. It is available in tablet form and should be taken orally with a full glass of water. It should be taken 30 to 40 minutes before sensual intercourse.