The effectiveness and duration of action of Extra Super Zhewitra, a medication used to treat erectile dysfunction and premature ejaculation, can vary from person to person due to several factors:

Metabolism: Individuals metabolize drugs at different rates based on their genetic makeup, liver function, and other physiological factors. A person with a faster metabolism may clear the medication from their system more quickly, resulting in a shorter duration of effectiveness.

Body weight and composition: Body weight and composition can influence how drugs are distributed and metabolized in the body. Generally, individuals with higher body weight may require higher doses of medication to achieve the same effect, which can affect the duration of effectiveness.

Overall health: Underlying health conditions such as liver or kidney disease can affect how drugs are processed and eliminated from the body, potentially altering the duration of effectiveness of Extra Super Zhewitra.

Tolerance: Long-term use of the medication can lead to tolerance, where the body becomes less responsive to the drug's effects over time. This may result in a shorter duration of effectiveness as the body adapts to the medication.

Interaction with other medications: Extra Super Zhewitra may interact with other medications a person is taking, either prolonging or shortening its effectiveness. It's essential to consider potential drug interactions when determining how long the medication will be effective.

Psychological factors: Psychological factors such as stress, anxiety, or depression can affect sexual performance and may influence how long the medication remains effective.

Individual variability: Lastly, individual variability in response to medications is common. What works well for one person may not work the same for another due to differences in biological and physiological factors.

Overall, the effectiveness and duration of action of Extra Super Zhewitra can vary from person to person due to a combination of these factors. It's essential for individuals to work closely with their healthcare provider to find the most effective dosage and treatment plan for their specific needs.