Individuals with a history of priapism should avoid using Fildena 100 (sildenafil) because priapism is a condition characterized by prolonged and painful erections unrelated to sexual stimulation. Sildenafil, the active ingredient in Fildena 100, works by increasing blood flow to the penis, which can exacerbate priapism in individuals prone to it. Priapism can lead to serious complications such as tissue damage and permanent erectile dysfunction. Therefore, it's crucial for individuals with a history of priapism to consult their healthcare provider before using medications like Fildena 100. Priapism is a medical condition characterized by prolonged and often painful erections that are not associated with sexual arousal or desire. It typically occurs when blood becomes trapped in the penis and is unable to drain properly. Priapism can be caused by various factors, including certain medical conditions, medications, and recreational drug use. Sildenafil, the active ingredient in Fildena 100mg and other similar medications used to treat erectile dysfunction, works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which increases blood flow to the penis, thereby facilitating erections. While this mechanism is beneficial for individuals with erectile dysfunction, it can pose risks for those with a history of priapism. In individuals prone to priapism, the increased blood flow caused by sildenafil can exacerbate the condition, leading to a prolonged and potentially dangerous erection. This prolonged erection can result in tissue damage to the penis and, if not treated promptly, may lead to permanent erectile dysfunction. Therefore, individuals with a history of priapism or predisposition to the condition should exercise caution when using medications like Fildena 100. It's essential for them to consult with a healthcare professional before starting any treatment for erectile dysfunction to discuss potential risks and determine the most appropriate course of action. In some cases, alternative treatments or lower doses of medication may be recommended to minimize the risk of priapism.